تفاعل #731440

معادلة التفاعل

5-fluoro-2-[2-(1-methylpiperidin-4-yloxy)-4-(pyrrolidin-1-yl)benzoylamino]-N-(3-methylpyridin-2-yl)benzamide trifluoroacetate

6-fluoro-2-[4-(pyrrolidin-1-yl)-2-(1-methylpiperidin-4-yloxy)phenyl]-4H-3,1-benzoxazin-4-one

2-amino-3-methylpyridine

→

5-Fluoro-2-[2-(1-methylpiperidin-4-yloxy)-4-(pyrrolidin-1-yl)-benzoylamino]-N-(3-methylpyridin-2-yl)benzamide

ظروف التفاعل

الإجراء التجريبي

Using methods substantially equivalent to those described in Example 118, 5-fluoro-2-[2-(1-methylpiperidin-4-yloxy)-4-(pyrrolidin-1-yl)benzoylamino]-N-(3-methylpyridin-2-yl)benzamide trifluoroacetate was prepared from 6-fluoro-2-[4-(pyrrolidin-1-yl)-2-(1-methylpiperidin-4-yloxy)phenyl]-4H-3,1-benzoxazin-4-one and 2-amino-3-methylpyridine.

المصدر