تفاعل #726049

معادلة التفاعل

4-methyl-2-amino benzothiazole

ethyl bromopyruvate

→

ethyl 5-methylimidazo[2,1-b]-benzthiazole-2-carboxylate

المردود 47.3%

ظروف التفاعل

المعالجة

1. 1
   أخرىEthyl 5-methylimidazo[2,1-b]-benzthiazole-2-carboxylate was prepared

الإجراء التجريبي

Ethyl 5-methylimidazo[2,1-b]-benzthiazole-2-carboxylate was prepared according to the procedure as outlined in Example 1, (Step 1). Starting from 4-methyl-2-amino benzothiazole (8.0 g, 48.7 m.mol) and ethyl bromopyruvate (14.0 g, 71.7 mmol), 6.0 g (45% Yield) of ethyl 5-methylimidazo[2,1-b]-benzthiazole-2-carboxylate was isolated as a brown solid. (M+H) 261.

المصدر