تفاعل #72533

معادلة التفاعل

trichloroacetyl chloride

pyrrole

potassium carbonate

→

title product

2,2,2-Trichloro-1-(1H-pyrrol-2-yl)ethanone

المذيبات

ethyl ether

water

ethyl ether

ظروف التفاعل

المعالجة

1. 1
   أخرىThe phases are separated
2. 2
   تجفيفthe organic phase is dried over sodium sulphate
3. 3
   ترشيحfiltered
4. 4
   workup.ADDITIONActive carbon is added to this organic phase
5. 5
   workup.STIRRINGAfter stirring for 5 minutes
6. 6
   ترشيحthe organic phase is filtered
7. 7
   أخرىevaporated to dryness

الإجراء التجريبي

To a solution of trichloroacetyl chloride (160.7 mmoles) in ethyl ether (26 ml) there is added, dropwise over a period of 3 hours, a solution of pyrrole (149 mmoles) in ethyl ether (83 ml). After stirring for a further hour, a solution of potassium carbonate (94 mmoles) in water (39 ml) is added dropwise. The phases are separated and the organic phase is dried over sodium sulphate and filtered. Active carbon is added to this organic phase. After stirring for 5 minutes, the organic phase is filtered and evaporated to dryness to yield the title product.

المصدر