تفاعل #713852

معادلة التفاعل

[2-(2,6-dichlorophenyl)-2H-pyrazolo[4,3-c]pyridine-4-yl]-(2,6-dimethylpyrimidin-4-yl)amine

4-chloro-2-(2,6-dichlorophenyl)-2H-pyrazolo[4,3-c]pyridine

2-chloro-6-methylpyrimidin-4-ylamine

→

title compound

المردود 57.0%

(2-Chloro-6-methylpyrimidin-4-yl)-[2-(2,6-dichlorophenyl)-2H-pyrazolo[4,3-c]pyridin-4-yl]amine

المردود 57.0%

ظروف التفاعل

المعالجة

1. 1
   أخرىwere reacted

الإجراء التجريبي

Following the procedure described above for [2-(2,6-dichlorophenyl)-2H-pyrazolo[4,3-c]pyridine-4-yl]-(2,6-dimethylpyrimidin-4-yl)amine, 4-chloro-2-(2,6-dichlorophenyl)-2H-pyrazolo[4,3-c]pyridine and 2-chloro-6-methylpyrimidin-4-ylamine were reacted to afford the title compound as a yellow solid (256 mg, 57% yield). 1H NMR (400 MHz, DMSO-d6): δ 11.06 (s, 1H), 9.14 (s, 1H), 8.51 (s, 1H), 8.02 (d, J=6.4 Hz, 1H), 7.84-7.80 (m, 2H), 7.73-7.68 (m, 1H), 7.30 (d, J=6.4 Hz, 1H), 2.46 (s, 3H). LCMS (Method D): RT=2.50 min, m/z: 407 [M+H+].

المصدر