تفاعل #71384

معادلة التفاعل

3-aminopyridine

8-(2,6-dichloro-3,5-dimethoxy-phenyl)-2-(4-ethyl-piperazin-1-ylmethyl)-quinoxaline-5-carboxylic acid

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Title compound

8-(2,6-Dichloro-3,5-dimethoxy-phenyl)-2-(4-ethyl-piperazin-1-ylmethyl)quinoxaline-5-carboxylic acid pyridin-3-ylamide

المذيبات

DCM MeOH

ظروف التفاعل

المعالجة

1. 1
   أخرىThe title compound was prepared in analogy to the procedure

الإجراء التجريبي

The title compound was prepared in analogy to the procedure described in Step 14.1 but using 3-aminopyridine, 8-(2,6-dichloro-3,5-dimethoxy-phenyl)-2-(4-ethyl-piperazin-1-ylmethyl)-quinoxaline-5-carboxylic acid (Step 83.1) and stirring the reaction mixture for 2 days at rt. Title compound: ESI-MS: 581.0/583.2 [M+H]+; tR=3.04 min (System 1); TLC: Rf=0.33 (DCM/MeOH, 9:1).

المصدر