تفاعل #706328

معادلة التفاعل

allyl bromide

ethyl salicylate

K2CO3

→

ethyl 2-(2-propenyloxy)benzoate

المردود 98.3%

المذيبات

DMF

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةThe reaction mixture was then heated on a steam bath for 2 hours
2. 2
   أخرىthe K2CO3 was removed by filtration
3. 3
   workup.ADDITIONthe reaction mixture was poured into water
4. 4
   استخلاصextracted with ethyl acetate (3×300 ml)
5. 5
   غسيلThe organic layer was washed with brine
6. 6
   تجفيفdried over MgSO4
7. 7
   أخرىthe solvent was removed

الإجراء التجريبي

To a solution of ethyl salicylate (100 g, 0.602 mol) in DMF (400 ml) was added K2CO3 (150 g), followed by the dropwise addition of allyl bromide (87.5 g, 0.723 mol). The reaction mixture was then heated on a steam bath for 2 hours, the K2CO3 was removed by filtration and the reaction mixture was poured into water and extracted with ethyl acetate (3×300 ml). The organic layer was washed with brine, and dried over MgSO4, and the solvent was removed to afford 122 g (98%) of ethyl 2-(2-propenyloxy)benzoate.

المصدر