تفاعل #70518

معادلة التفاعل

4-(1,1-Dimethylethyl) 2-(phenylmethyl) 2,4-morpholinedicarboxylate

Hydrogen chloride

→

title compound

المردود 110.9%

Phenylmethyl 2-morpholinecarboxylate

المردود 110.9%

المذيبات

1,4-dioxane

1,4-dioxane

ظروف التفاعل

المعالجة

1. 1
   أخرىThe solvent was removed in vacuo
2. 2
   أخرىto give a white solid
3. 3
   أخرىThe solid was dried in a vacuum oven overnight

الإجراء التجريبي

4-(1,1-Dimethylethyl) 2-(phenylmethyl) 2,4-morpholinedicarboxylate (1.19 g, 3.70 mmol) was dissolved in 1,4-dioxane (2 ml). Hydrogen chloride (4M) in 1,4-dioxane (20 ml, 80 mmol) was added and the mixture was stirred at room temperature under nitrogen for 4 hr. The solvent was removed in vacuo to give a white solid. The solid was dried in a vacuum oven overnight to give the title compound (908 mg) as a white solid.

المصدر