تفاعل #70261

معادلة التفاعل

2-methoxy-5-nitro-3-phenylpyridine

→

expected product

6-Methoxy-5-phenylpyridin-3-amine

المذيبات

ethanol

ظروف التفاعل

المعالجة

1. 1
   ترشيحThe catalyst was filtered off
2. 2
   غسيلthe solid thoughtfully washed with warm ethanol
3. 3
   أخرىThe filtrate was evaporated
4. 4
   أخرىaffording

الإجراء التجريبي

A mixture of 2-methoxy-5-nitro-3-phenylpyridine (0.43 mmol, 0.1 g) and Pd/C 10% (0.14 mmol, 0.015 g) in ethanol (2 ml) was stirred for 16 hours under hydrogen atmosphere. The catalyst was filtered off and the solid thoughtfully washed with warm ethanol. The filtrate was evaporated affording 0.085 g (98% of yield) of the expected product.

المصدر