تفاعل #701487

معادلة التفاعل

palmitoyl chloride

n-butylamine

→

N-n-butyl-hexadecanamide

المذيبات

ethyl ether

ethyl ether

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةunder gentle reflux for one hour
2. 2
   ترشيحThe precipitate was filtered off
3. 3
   غسيلthoroughly washed with water
4. 4
   أخرىThe reaction product was recrystallized from ethanol giving 148.4 g of the title compound, melting point 74°-76° C.

الإجراء التجريبي

An amount of 137.4 g of palmitoyl chloride in 100 ml of ethyl ether was added, under stirring at room temperature, to 80.5 g of n-butylamine in 700 ml of ethyl ether. Stirring was continued under gentle reflux for one hour. The precipitate was filtered off and thoroughly washed with water. The reaction product was recrystallized from ethanol giving 148.4 g of the title compound, melting point 74°-76° C.

المصدر