تفاعل #70088

ord-bb176405ee3c4692be973994088b8f98

الكواشف

لا شيء

المذيبات

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

المعالجة

  1. 1
    درجة الحرارةto reflux
  2. 2
    درجة الحرارةthe medium is again heated
  3. 3
    درجة الحرارةat reflux
  4. 4
    درجة الحرارةby refluxing

الإجراء التجريبي

8 g of dichloropivalic acid are placed in a 250 ml three-necked flask on which is mounted a condenser and a dropping funnel. The acid is dissolved in 80 ml of water, slowly adding 4.6 g of Na2CO3. A solution of 10.7 g of potassium thioacetate is added dropwise and the reaction medium is brought to reflux. 14.9 g of Na2CO3 are added and the medium is again heated at reflux. After disappearance of the starting material, 7.3 ml of DMSO are added, followed by refluxing. The dithiolane is obtained after acidification by precipitation and drying of the solid under vacuum. A pale yellow solid is obtained.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US08535647B2uspto-grants-2013_09