تفاعل #70033

ord-9b7607480a724b22ad1020f17427cdb2

معادلة التفاعل

[C-]#[N+]CC(C)(C)OC(=O)OC
1-isocyano-2-methylpropan-2-yl methyl carbonate
Nc1ccc2[nH]cnc2c1
1H-benzo[d]imidazol-5-amine
CCCCOc1ccc(C=O)cc1
4-butoxybenzaldehyde
CC(C)(C)[O-].[Na+]
sodium tert.-butoxide
CCOC(=O)CC(=O)O
2-(ethoxycarbonyl)acetic acid
CCCCOc1ccc(C2C(=O)CC(=O)N2c2ccc3[nH]cnc3c2)cc1
1-(1H-Benzo[d]imidazol-5-yl)-5-(4-butoxyphenyl)-pyrrolidine-2,4-dione

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

المعالجة

  1. 1
    أخرىThe compound was synthesized

الإجراء التجريبي

The compound was synthesized starting from 1H-benzo[d]imidazol-5-amine (0.798 g, 6 mmol), 4-butoxybenzaldehyde (1.0 g, 6 mmol), 2-(ethoxycarbonyl)acetic acid (0.79 g, 6 mmol), 1-isocyano-2-methylpropan-2-yl methyl carbonate (0.943 g, 6 mmol) and sodium tert.-butoxide (0.572 g, 5 mmol) according to method 3.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US08530670B2uspto-grants-2013_09