تفاعل #70032

معادلة التفاعل

1-isocyano-2-methylpropan-2-yl methyl carbonate

1H-benzo[d]imidazol-5-amine

4-(4,4-difluorobutoxy)benzaldehyde

sodium tert.-butoxide

2-(ethoxycarbonyl)acetic acid

→

1-(1H-Benzo[d]imidazol-5-yl)-5-(4-(4,4-difluorobutoxy)phenyl)-pyrrolidine-2,4-dione

ظروف التفاعل

المعالجة

1. 1
   أخرىThe compound was synthesized

الإجراء التجريبي

The compound was synthesized starting from 1H-benzo[d]imidazol-5-amine (0.620 g, 4.6 mmol), 4-(4,4-difluorobutoxy)benzaldehyde (1.0 g, 4.6 mmol), 2-(ethoxycarbonyl)acetic acid (0.61 g, 4.6 mmol), 1-isocyano-2-methylpropan-2-yl methyl carbonate (0.72 g, 4.6 mmol) and sodium tert.-butoxide (0.620 g, 5.5 mmol) according to method 3.

المصدر