تفاعل #70030

معادلة التفاعل

ethyl 2-[(1H-benzo[d]imidazol-5-yl)({[4-(morpholin-4-yl)phenyl]({2-[(methoxycarbonyl)oxy]-2-ethylpropyl}carbamoyl)methyl})-carbamoyl]acetate

potassium tert.-butoxide

→

Ethyl 1-(1H-benzo[d]imidazol-5-yl)-5-(4-morpholinophenyl)-2,4-dioxopyrrolidine-3-carboxylate

ظروف التفاعل

المعالجة

1. 1
   أخرىThe compound was synthesized
2. 2
   أخرىmay be prepared in accordance with the procedure

الإجراء التجريبي

The compound was synthesized starting from ethyl 2-[(1H-benzo[d]imidazol-5-yl)({[4-(morpholin-4-yl)phenyl]({2-[(methoxycarbonyl)oxy]-2-ethylpropyl}carbamoyl)methyl})-carbamoyl]acetate (which may be prepared in accordance with the procedure described for Intermediate 4; 0.38 g, 0.638 mmol) and potassium tert.-butoxide solution (1M, 1.276 ml, 1.276 mmol) according to the method described in Step 2.

المصدر