تفاعل #69609

معادلة التفاعل

2-amino-4-methyl-6-tertbutylphenol

pyridine-2-carbaldehyde

→

12

المردود 107.2%

2-Phenoxy-3-tert-butyl-5-methyl-N-[(1E)-2-pyridylmethylene]aniline

المردود 107.2%

المذيبات

methanol

methanol

ظروف التفاعل

المعالجة

1. 1
   أخرىforming a dark orange solution
2. 2
   أخرىquickly forming a yellow precipitate
3. 3
   أخرىcollected on a frit
4. 4
   غسيلwashed with cold methanol
5. 5
   أخرىdried under vacuum

الإجراء التجريبي

To a slurry of 2-amino-4-methyl-6-tertbutylphenol (0.70 g, 3.90 mmol) in 5 mL methanol, a methanol solution of pyridine-2-carbaldehyde (0.418 g, 3.90 mmol) was slowly added, forming a dark orange solution. Two drops formic acid were added, quickly forming a yellow precipitate. This was stirred for 2 hr, then collected on a frit, washed with cold methanol and dried under vacuum to yield 0.72 g of 12 (69%).

المصدر