تفاعل #689437

معادلة التفاعل

3-nitro[1,5]naphthyridin-4-amine

[1,5]naphthyridine-3,4-diamine

quinoline-3,4-diamine

3-nitroquinolin-4-amine

→

1H-imidazo[4,5-c][1,5]naphthyridine

1H-imidazo[4,5-c]quinoline

ظروف التفاعل

الإجراء التجريبي

In steps (2) and (3) of Reaction Scheme VI, a 3-nitroquinolin-4-amine or 3-nitro[1,5]naphthyridin-4-amine of Formula LII is first reduced to a quinoline-3,4-diamine or [1,5]naphthyridine-3,4-diamine of Formula LIII, which is then treated with a carboxylic acid equivalent to provide a 1H-imidazo[4,5-c]quinoline or 1H-imidazo[4,5-c][1,5]naphthyridine of Formula LIV. Steps (2) and (3) of Reaction Scheme VI can be carried out according to the methods described in steps (2) and (3) of Reaction Scheme I.

المصدر