تفاعل #689436

معادلة التفاعل

3-nitro[1,5]naphthyridin-4-amine

[1,5]naphthyridine-3,4-diamine

quinoline-3,4-diamine

3-nitroquinolin-4-amine

→

1H-imidazo[4,5-c][1,5]naphthyridine

1H-imidazo[4,5-c]quinoline

ظروف التفاعل

الإجراء التجريبي

In steps (2) and (3) of Reaction Scheme V, a 3-nitroquinolin-4-amine or 3-nitro[1,5]naphthyridin-4-amine of Formula XLIII is first reduced to a quinoline-3,4-diamine or [1,5]naphthyridine-3,4-diamine of Formula XLIV, which is then treated with a carboxylic acid equivalent to provide a 1H-imidazo[4,5-c]quinoline or 1H-imidazo[4,5-c][1,5]naphthyridine of Formula XLV. Steps (2) and (3) of Reaction Scheme V can be carried out according to the methods described in steps (2) and (3) of Reaction Scheme I.

المصدر