تفاعل #68701

معادلة التفاعل

octadecyl 4-nitrobenzoate

→

octadecyl 4-aminobenzoate

المردود 84.0%

المذيبات

ethyl acetate

ظروف التفاعل

المعالجة

1. 1
   أخرىUnder a nitrogen purge
2. 2
   أخرىfor sixteen hours
3. 3
   ترشيحAdded chloroform and filtered the reaction mixture through a layer of CELITE
4. 4
   ترشيحfilter aid
5. 5
   تركيزThe filtrate was concentrated under reduced pressure to light tan solid
6. 6
   أخرىThe solid was recrystallized from ethanol

الإجراء التجريبي

Under a nitrogen purge, 10% platinum on carbon (2.0 grams) was added to a mixture of octadecyl 4-nitrobenzoate (23 grams, 55 mmol) and ethyl acetate (230 milliliters) in a Parr vessel. The vessel was placed under hydrogen pressure (49 psi, 3.3×105 Pa) for sixteen hours. Added chloroform and filtered the reaction mixture through a layer of CELITE filter aid. The filtrate was concentrated under reduced pressure to light tan solid. The solid was recrystallized from ethanol to obtain 18 grams of octadecyl 4-aminobenzoate as a white solid.

المصدر