تفاعل #684948

معادلة التفاعل

Thionyl chloride

4-n-butylbenzyl alcohol

→

title compound

المردود 104.9%

1-(Chloromethyl)-4-n-butylbenzene

المردود 104.9%

المذيبات

ether

ظروف التفاعل

المعالجة

1. 1
   أخرىAfter concentration of the mixture, excess thionyl chloride was removed by azeotropic distillation with benzene

الإجراء التجريبي

Thionyl chloride (2.5 ml, 34 mmol) was added to a solution of 4-n-butylbenzyl alcohol (2.0 g, 12 mmol) in ether (25 ml), and this mixture was stirred at room temperature for 3 hours. After concentration of the mixture, excess thionyl chloride was removed by azeotropic distillation with benzene to give the title compound (2.3 g). This compound was used in the following reaction without purification.

المصدر