تفاعل #684939

معادلة التفاعل

4-methoxy-4′-(di-p-tolylamino)stilbene

sodium ethanethiolate

water

hydrochloric acid

→

4-hydroxy-4′-(di-p-tolylamino)stilbene

المذيبات

N,N-dimethylformamide

ظروف التفاعل

المعالجة

1. 1
   أخرىreacted for 5 hours at 130° C
2. 2
   درجة الحرارةThe mixture is cooled down
3. 3
   استخلاصThe objective material is extracted
4. 4
   غسيلThe extracted liquid is washed with water
5. 5
   أخرىdried
6. 6
   أخرىThe crude objective material is prepared
7. 7
   أخرىby removing the solvent (i.e., N,N-dimethylformamide)
8. 8
   أخرىFurther, the crude objective material is purified with a column chromatography

الإجراء التجريبي

The above-prepared 4-methoxy-4′-(di-p-tolylamino)stilbene and twice equimolar amount of sodium ethanethiolate are dissolved in N,N-dimethylformamide, and reacted for 5 hours at 130° C. The mixture is cooled down, and then poured into water and neutralized with hydrochloric acid. The objective material is extracted therefrom using acetic acid. The extracted liquid is washed with water, and then dried. The crude objective material is prepared by removing the solvent (i.e., N,N-dimethylformamide) therefrom. Further, the crude objective material is purified with a column chromatography using silica gel. Thus, 4-hydroxy-4′-(di-p-tolylamino)stilbene (i.e., objective material) is prepared.

المصدر