تفاعل #675846

ord-59cb7952e5b64d128472d09d0d0ad4f1

معادلة التفاعل

Cc1n[nH]c(C)c1B1OC(C)(C)C(C)(C)O1
3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
OCC12CC3CC(CC(Br)(C3)C1)C2
3-bromo-1-adamantanemethanol
OCC12CC3CC(CC(C3)C1)C2
1-adamantanemethanol
Brc1ccn(CC23CC4CC(CC(C4)C2)C3)n1
title compound
Brc1ccn(CC23CC4CC(CC(C4)C2)C3)n1
3-bromotricyclo[3.3.1.13,7]dec-1-ylmethyl-1H-pyrazole

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

الإجراء التجريبي

The title compound was prepared by substituting pyrazole for 3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole and 3-bromo-1-adamantanemethanol for 1-adamantanemethanol in EXAMPLE 2A.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US09227963B2uspto-grants-2016_01