تفاعل #674287

ord-9fb1ff1cb2d94f1da5086a474289cc48

معادلة التفاعل

[Ca+2].[Cl-].[Cl-]
calcium chloride
O=P([O-])([O-])O
hydrogen phosphate
[Na+].[OH-]
NaOH
O=P([O-])([O-])[O-].O=P([O-])([O-])[O-].[Ca+2].[Ca+2].[Ca+2]
Calcium Phosphate

الكواشف

لا شيء

المذيبات

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

المعالجة

  1. 1
    أخرىCaP NPs
  2. 2
    أخرىwere obtained by filtration of the suspension through a 0.22 μm
  3. 3
    ترشيحfilter
  4. 4
    أخرىCaP NPs
  5. 5
    أخرىwere stored at 4° C. before use
  6. 6
    أخرىCaP/ZOL-NPs complexes (CaPZ NPs) were prepared

الإجراء التجريبي

An aqueous solution of calcium chloride (18 mM) was added, dropwise and under magnetic stirring, to an aqueous solution on dibasic hydrogen phosphate (10.8 mM). The pH of both solutions was adjusted beforehand to 9.5 with NaOH. CaP NPs were obtained by filtration of the suspension through a 0.22 μm filter. CaP NPs were stored at 4° C. before use. CaP/ZOL-NPs complexes (CaPZ NPs) were prepared by mixing a CaP NPs dispersion with an aqueous solution of (50 mg/ml of ZOL in phosphate buffer at pH 9.5), at a volume ratio of 50:1.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US09226897B2uspto-grants-2016_01