تفاعل #67120

معادلة التفاعل

1,1-dimethylethyl 6-oxa-9-azaspiro[4.5]decane-9-carboxylate

trifluoroacetic acid

→

title compound

المردود 173.4%

6-Oxa-9-azaspiro[4.5]decane

المردود 173.4%

المذيبات

DCM

ظروف التفاعل

المعالجة

1. 1
   أخرىThe solvent was evaporated

الإجراء التجريبي

To a of solution 1,1-dimethylethyl 6-oxa-9-azaspiro[4.5]decane-9-carboxylate (200 mg, 0.829 mmol, available from Tyger Scientific Inc) in DCM (3 ml) was added trifluoroacetic acid (TFA) (0.5 ml). The resulting colourless yellow solution was stirred at room temperature for 24 hr. The solvent was evaporated to give the title compound as a grey oil (203 mg).

المصدر