تفاعل #669956

معادلة التفاعل

bromine

N-(4-nitrophenyl)-4-methylbenzenesulphonamide

cyclopentylmagnesium chloride

triethylamine

→

expected product

N-(2-Bromo-5-cyclopentyl-4-nitrophenyl)-4-methylbenzenesulphonamide

المذيبات

THF

ether

ظروف التفاعل

المعالجة

1. 1
   أخرىThis compound is prepared

الإجراء التجريبي

This compound is prepared according to the procedure described in step A of Preparation 2.18, from 15 g of N-(4-nitrophenyl)-4-methylbenzenesulphonamide in 100 ml of THF and 64 ml of a 2M solution of cyclopentylmagnesium chloride in ether, followed by 6.8 ml of bromine and 35 ml of triethylamine. 6.1 g of the expected product are obtained, m.p.=122° C.

المصدر