تفاعل #66913

معادلة التفاعل

Compound 51

Dibenzyl 2-(3-fluorophenyl)-6-methoxy-4-oxo-1,4-dihydroquinolin-5-yl phosphate

compound 49

2-(3-Fluorophenyl)-6-methoxyquinoline-4,5-diyl bis(dihydrogen phosphate)

→

52

المردود 63.7%

2-(3-Fluorophenyl)-6-methoxy-4-oxo-1,4-dihydroquinolin-5-yl dihydrogen phosphate

المردود 63.7%

ظروف التفاعل

المعالجة

1. 1
   أخرىto react in the same manner

الإجراء التجريبي

Compound 51 (0.25 g, 0.46 mmol) was allowed to react in the same manner as described in the preparation of compound 49 to give 52. Yellow solid; yield: 63.7%; mp 179-181° C.; MS (ESI): m/z 366 (M+H)+; 1H-NMR (D2O+NaOD, 200 MHz): δ 3.76 (s, 3H), 6.53 (s, 1H), 7.05 (1, =8.4 Hz, 1H), 7.24-7.60 (m, 5H); Anal. (C16H13FNO6P) C, H, N.

المصدر