تفاعل #65990

معادلة التفاعل

2-methyl-5-(2-benzothiazolylmethoxy)-1H-indole-3-acetic acid ethyl ester

4chlorobenzyl chloride

→

title compound

1-[(4-Chlorophenyl)methyl]-2-methyl-5-(2-benzothiazolylmethoxy)-1H-indole-3-acetic acid

المذيبات

methanol

ظروف التفاعل

المعالجة

1. 1
   أخرىRecrystallization from acetonitrile
2. 2
   أخرىaffords white crystals, m.p. 175°-176° C.

الإجراء التجريبي

The title compound is prepared according to the method of Example 16 using 2-methyl-5-(2-benzothiazolylmethoxy)-1H-indole-3-acetic acid ethyl ester and 4chlorobenzyl chloride; however, the hydrolysis is carried out in aqueous methanol. Recrystallization from acetonitrile affords white crystals, m.p. 175°-176° C.

المصدر