تفاعل #65768

معادلة التفاعل

acetic acid

2-bromo-3,4-diethoxycarbonyl-5-nitro-6-phenylpyridine

→

3-Amino-6-bromo-4,5-diethoxycarbonyl-2-phenylpyridine

المذيبات

ethanol

ظروف التفاعل

المعالجة

1. 1
   workup.ADDITIONwas added
2. 2
   درجة الحرارةthe mixture was refluxed for 1 hour

الإجراء التجريبي

In 25 ml of ethanol was dissolved 550 mg of 2-bromo-3,4-diethoxycarbonyl-5-nitro-6-phenylpyridine, whereto 0.36 g (5 eq.) of reduced iron was added, followed by heating to 60° C. After 1.5 ml (16 eq.) of acetic acid was added dropwise, the mixture was refluxed for 1 hour.

المصدر