تفاعل #65760

معادلة التفاعل

water

3,4-diethoxycarbonyl-6-(4-methoxyphenyl)-2(1H)pyridone

nitric acid

→

3,4-Diethoxycarbonyl-6-(4-methoxyphenyl)-5-nitro-2(1H)pyridone

المذيبات

acetic anhydride

ظروف التفاعل

المعالجة

1. 1
   workup.STIRRINGstirring
2. 2
   workup.WAITwas continued for further 1 hour
3. 3
   ترشيحThe viscous product was collected by filtration
4. 4
   أخرىcrystallized with diethyl ether
5. 5
   غسيلwashed

الإجراء التجريبي

In 8 ml of acetic anhydride was suspended 1.2 g of 3,4-diethoxycarbonyl-6-(4-methoxyphenyl)-2(1H)pyridone. After the mixture was cooled to -30° C. 0 36 ml of fuming nitric acid was added dropwise, followed by stirring for 45 minutes. After water was added, stirring was continued for further 1 hour. The viscous product was collected by filtration, crystallized with diethyl ether and washed.

المصدر