تفاعل #655066

معادلة التفاعل

3-(4-methoxyphenyl)propan-1-ol

pyridinium chlorochromate

→

subtitle compound

المردود 45.9%

3-(4-Methoxyphenyl)propanal

المردود 45.9%

المذيبات

dichloromethane

dichloromethane

ظروف التفاعل

المعالجة

1. 1
   ترشيحthen filtered through a kieselguhr pad
2. 2
   غسيلThe residue was washed with ether (3×500 ml)
3. 3
   أخرىthe combined liquors were evaporated under reduced pressure
4. 4
   workup.DISTILLATIONThe residual oil was purified by vacuum distillation

الإجراء التجريبي

A solution of 3-(4-methoxyphenyl)propan-1-ol (15.02 g) in dichloromethane (100 ml) was added to a stirred suspension of pyridinium chlorochromate (29 g) in dichloromethane (250 ml). The mixture was stirred for 2 hours then filtered through a kieselguhr pad. The residue was washed with ether (3×500 ml) and the combined liquors were evaporated under reduced pressure. The residual oil was purified by vacuum distillation to give the subtitle compound (6.81 g) as an oil.

المصدر