تفاعل #65428

معادلة التفاعل

3-methyl-4-phenylthiobenzoic acid

sulfuric acid

methanol

→

methyl 3-methyl-4-phenylthiobenzoate

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةwas refluxed for 4 hours
2. 2
   أخرىAfter reaction
3. 3
   تركيزthe reaction mixture was concentrated in vacuo, and 1.5 liters of ethyl acetate
4. 4
   workup.ADDITIONwas added to the residue
5. 5
   غسيلthe mixture was washed with saturated brine (400 ml×3)
6. 6
   تجفيفdried with anhydrous sodium sulfate
7. 7
   تركيزconcentrated in vacuo

الإجراء التجريبي

A mixture was 85 g of 3-methyl-4-phenylthiobenzoic acid, 20 ml of concentrated sulfuric acid, and 1.2 liters of methanol was refluxed for 4 hours while stirring. After reaction, the reaction mixture was concentrated in vacuo, and 1.5 liters of ethyl acetate was added to the residue, and the mixture was washed with saturated brine (400 ml×3), and dried with anhydrous sodium sulfate, concentrated in vacuo, and methyl 3-methyl-4-phenylthiobenzoate was obtained (80.33 g).

المصدر