تفاعل #6536

معادلة التفاعل

2-(4-acetaminophenoxy)-2-methyl propionic acid

acetic acid

→

2-(4-aminophenoxy)-2-methyl propionic acid

المردود 62.0%

المذيبات

KOH

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةThe solution is then cooled

الإجراء التجريبي

1.18 g (0.005 mol) of the 2-(4-acetaminophenoxy)-2-methyl propionic acid is boiled in 10% KOH (60 ml) for 1/2 hour. The solution is then cooled and acidified with acetic acid to yield 0.6 g (62% yield) of 2-(4-aminophenoxy)-2-methyl propionic acid as a yellowish white powder, mp 214°-16° C.

المصدر