تفاعل #64972

معادلة التفاعل

7-acetyl-1,2-dimethyl-3-oxa-2,7-diazabicyclo[3.3.0]octane

NaOH

K2CO3

→

1,2-Dimethyl-3-oxa-2,7-diazabicyclo[3.3.0]octane

المذيبات

water

ظروف التفاعل

المعالجة

1. 1
   استخلاصextracted several times with CHCl3
2. 2
   تجفيفthe extract is dried over K2CO3
3. 3
   تركيزconcentrated
4. 4
   workup.DISTILLATIONthe residue is distilled

الإجراء التجريبي

11.8 g (64mmol) of 7-acetyl-1,2-dimethyl-3-oxa-2,7-diazabicyclo[3.3.0]octane are heated under reflux with 12 g of NaOH in 36 ml of water overnight. The mixture is saturated with K2CO3 and extracted several times with CHCl3, the extract is dried over K2CO3 and concentrated and the residue is distilled.

المصدر