تفاعل #64951

معادلة التفاعل

water

pyridine-2,3-dicarboxylic acid N-benzylimide

methyl iodide

→

1-Methyl-pyridinium-2,3-dicarboxylic acid N-benzylimide iodide

المذيبات

nitromethane

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةwhile heating
2. 2
   درجة الحرارةwhile cooling
3. 3
   درجة الحرارةunder reflux
4. 4
   درجة الحرارةAfter cooling
5. 5
   ترشيحthe solid is filtered off with suction
6. 6
   غسيلwashed with methylene chloride
7. 7
   أخرىare obtained

الإجراء التجريبي

190.5g (0.8 mol) of pyridine-2,3-dicarboxylic acid N-benzylimide are dissolved in 800 ml of nitromethane, while heating, and 136 g (0.96 mol) of methyl iodide are added dropwise. The mixture is then boiled for 8 hours while cooling under reflux (cooling water 0° C.). After cooling, the solid is filtered off with suction and washed with methylene chloride. 123 g of dark red crystals having a melting point of 162°-165° C. (decomposition) are obtained.

المصدر