تفاعل #64673

معادلة التفاعل

1-Chloro-4-hydroxythioxanthone

potassium carbonate

n-Propyl bromide

→

title compound

المردود 75.5%

1-Chloro-4-n-propoxythioxanthone

المردود 75.5%

المذيبات

acetone

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةthe resulting mixture heated
2. 2
   درجة الحرارةunder reflux for 16 hours
3. 3
   درجة الحرارةThe mixture was then cooled
4. 4
   أخرىquenched on to water (250 ml)
5. 5
   ترشيحThe solid was filtered
6. 6
   غسيلwashed with water the resulting damp solid
7. 7
   أخرىrecrystallised from ethanol (50 ml)

الإجراء التجريبي

1-Chloro-4-hydroxythioxanthone (7.8 g; 0.03 mol) prepared as above and potassium carbonate (5.0 g; 0.036 mol) was stirred and refluxed for 10 minutes in acetone (50 ml). n-Propyl bromide (5.5 g; 0.045 mol) was added and the resulting mixture heated under reflux for 16 hours. The mixture was then cooled and quenched on to water (250 ml). The solid was filtered and washed with water the resulting damp solid recrystallised from ethanol (50 ml) to afford the title compound (6.9 g; 75.5%) of mp 102°-3°. Analysis C16H13ClO2S=304.777 Requires C 63.05%; H 4.30%; Cl 11.63%; S 10.52% Found C 63.14%; H 4.37%; Cl 11.66%; S 10.63%

المصدر