تفاعل #64356

معادلة التفاعل

N-methyl-6-nitro-2,2-dimethyl-2H-1-benzopyran-4-carboxamide

ethyl iodide

hydride

tetrahydrofuran

Dichloromethane

→

N-ethyl-N-methyl-6-nitro-2,2-dimethyl-2H-1-benzopyran-4-carboxamide

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةwas heated
2. 2
   درجة الحرارةat reflux for 30 minutes
3. 3
   أخرىany insoluble matter was removed by filtration
4. 4
   أخرىThe filtrate was recrystallized from a mixture of diethyl ether and n-hexane

الإجراء التجريبي

A mixture of 0.53 g of N-methyl-6-nitro-2,2-dimethyl-2H-1-benzopyran-4-carboxamide, 1.60 g of ethyl iodide, 0.09 g of sodlum hydride, and 10 ml of tetrahydrofuran was heated at reflux for 30 minutes. Dichloromethane was added to the reaction mixture, and any insoluble matter was removed by filtration. The filtrate was recrystallized from a mixture of diethyl ether and n-hexane to obtain 0.45 g of N-ethyl-N-methyl-6-nitro-2,2-dimethyl-2H-1-benzopyran-4-carboxamide represented by formula shown below.

المصدر