تفاعل #6428

معادلة التفاعل

2,3-difluoro-4-(trans-4-pentylcyclohexyl)methoxyphenol

butyl bromide

potassium carbonate

→

1-butyloxy-2,3-difluoro-4-(trans-4-pentylcyclohexyl)methoxybenzene

المذيبات

dimethylformamide

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةAfter cooling
2. 2
   ترشيحthe inorganic salts are filtered off with suction
3. 3
   تركيزthe filtrate is concentrated
4. 4
   workup.ADDITIONwater is added

الإجراء التجريبي

0.1 mol of 2,3-difluoro-4-(trans-4-pentylcyclohexyl)methoxyphenol, 0.11 mol of butyl bromide and 0.11 mol of potassium carbonate are heated for 16 hours at 100° in 100 ml of dimethylformamide (DMF). After cooling, the inorganic salts are filtered off with suction, the filtrate is concentrated, and water is added. 1-butyloxy-2,3-difluoro-4-(trans-4-pentylcyclohexyl)methoxybenzene is obtained by extraction with dichloromethane.

المصدر