تفاعل #63288

ord-5116b757d2fc4b29bf10d174261fb24e

معادلة التفاعل

COc1ccc(C(CCN2CCCCC2)NC(=O)Cc2ccc3ccccc3n2)cc1
N-[1-(4-methoxyphenyl)-3-piperidinopropyl]quinaldinamide
O.O.O=C(O)C(=O)O
oxalic acid dihydrate
COc1ccc(C(CCN2CCCCC2)NC(=O)Cc2ccc3ccccc3n2)cc1.O=C(O)C(=O)O
subject compound
المردود 70.0%
COc1ccc(C(CCN2CCCCC2)NC(=O)Cc2ccc3ccccc3n2)cc1.O=C(O)C(=O)O
N-[1-(4-methoxyphenyl)-3-piperidinopropyl]quinaldinamide oxalate
المردود 70.0%

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

الإجراء التجريبي

The procedure of Example 7 was repeated using 1.03 g (2.56 mmol.) of N-[1-(4-methoxyphenyl)-3-piperidinopropyl]quinaldinamide and 323 mg (2.56 mmol.) of oxalic acid dihydrate, to obtain 884 mg (yield: 70%) of the subject compound as a white powdery product upon recrystallization from 8 ml of ethanol.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US04764617uspto-grants-1988_08