تفاعل #63286

ord-d189332df8ad49bc8a8152b0d3067aa0

معادلة التفاعل

Cc1ccc(C(CCN2CCCCC2)NC(=O)Cc2ccc3ccccc3n2)cc1
N-[1-(4-methylphenyl)-3-piperidinopropyl]quinaldinamide
O.O.O=C(O)C(=O)O
oxalic acid dihydrate
Cc1ccc(C(CCN2CCCCC2)NC(=O)Cc2ccc3ccccc3n2)cc1.O=C(O)C(=O)O
subject compound
المردود 80.0%
Cc1ccc(C(CCN2CCCCC2)NC(=O)Cc2ccc3ccccc3n2)cc1.O=C(O)C(=O)O
N-[1-(4-methylphenyl)-3-piperidinopropyl]quinaldinamide oxalate
المردود 80.0%

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

الإجراء التجريبي

The procedure of Example 7 was repeated using 917 mg (2.36 mmol.) of N-[1-(4-methylphenyl)-3-piperidinopropyl]quinaldinamide and 298 mg (2.36 mmol.) of oxalic acid dihydrate, to obtain 901 mg (yield: 80%) of the subject compound as a whilte crystalline product upon recrystallization from 8 ml of ethanol.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: US04764617uspto-grants-1988_08