تفاعل #631971
ord-43b48e2ce5cd45609b530a2602e1348d
معادلة التفاعل
2-Carboxyethyl acrylate
Thionyl chloride
→
desired product
3-chloro-3-oxopropyl acrylate
المتفاعلات
الكواشف
لا شيء
المذيبات
ظروف التفاعل
الظروف التفصيلية
See reaction.notes.procedure_details.
المعالجة
- 1درجة الحرارةthe solution is cooled in an ice bath
- 2أخرىThe solvent is removed under reduced pressure
الإجراء التجريبي
2-Carboxyethyl acrylate (1 eq.) is dissolved in CH2Cl2 and the solution is cooled in an ice bath. Thionyl chloride (1 eq.) is added dropwise and the mixture is allowed to warm to room temperature and stir for 4 hours. The solvent is removed under reduced pressure and the desired product is isolated by vacuum distillation.