تفاعل #6306
ord-5c4084f677714fefb5da04262b23b483
معادلة التفاعل
2-(4-methylphenyl)benzoxazole
N-bromosuccinimide
benzoyl peroxide
→
2-(4-Bromomethylphenyl)benzoxazole
الكواشف
لا شيء
ظروف التفاعل
الظروف التفصيلية
See reaction.notes.procedure_details.
المعالجة
- 1درجة الحرارةat reflux for 20 hours
- 2أخرىthe solid byproducts are removed by filtration
- 3تركيزThe filtrate is concentrated in vacuo
- 4أخرىthe product is purified by recrystallization from benzene
الإجراء التجريبي
A stirred solution of 20.9 g (0.1 mole) of 2-(4-methylphenyl)benzoxazole, 17.8 g (0.1 mole) of N-bromosuccinimide, and 0.4 g (0.2 mole %) of benzoyl peroxide in carbon tetrachloride is heated at reflux for 20 hours. After cooling to room temperature, the reaction is diluted by the addition of carbon tetrachloride, and the solid byproducts are removed by filtration. The filtrate is concentrated in vacuo, and the product is purified by recrystallization from benzene.