تفاعل #6299

معادلة التفاعل

4-triflyltoluene

N-bromosuccinimide

benzoyl peroxide

→

4-Triflyl-alpha-bromotoluene

المذيبات

carbon tetrachloride

carbon tetrachloride

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةat reflux for 20 hours
2. 2
   أخرىthe solid byproducts are removed by filtration
3. 3
   تركيزThe filtrate is concentrated in vacuo
4. 4
   أخرىthe product is purified by recrystallization from benzene

الإجراء التجريبي

A stirred solution of 22.4 g (0.1 mole) of 4-triflyltoluene, 178 g (0.1 mole) of N-bromosuccinimide, and 0.48 g (0.2 mole %) of benzoyl peroxide in carbon tetrachloride is heated at reflux for 20 hours. After cooling to room temperature, the reaction is diluted by the addition of carbon tetrachloride, and the solid byproducts are removed by filtration. The filtrate is concentrated in vacuo, and the product is purified by recrystallization from benzene.

المصدر