تفاعل #62969

معادلة التفاعل

potassium

4-hydroxy-4'-nitrobiphenyl

6-iodo-1-hexanol

18-crown-6 ether

potassium

→

4-(6-Hydroxyhexyloxy)-4'-nitrobiphenyl

المذيبات

toluene

ظروف التفاعل

المعالجة

1. 1
   workup.DISSOLUTIONhas dissolved
2. 2
   أخرىreacted
3. 3
   ترشيحThe solution is filtered hot
4. 4
   أخرىAfter solvent removal
5. 5
   أخرىthe solid residue is recrystallized from ethanol
6. 6
   أخرىto yield a purified product, m.p. 117°-119° C.

الإجراء التجريبي

To 500 ml of toluene in a one liter round bottom flask, fitted with a condenser and magnetic stirrer, are added 7.6 g (0.03M) of the potassium salt of 4-hydroxy-4'-nitrobiphenyl, 4.9 g (0.035M) of 6-iodo-1-hexanol, and 0.5 g of 18-crown-6 ether. The mixture is refluxed for about 20 hours until all of the potassium salt has dissolved and reacted as evidenced by the absence of the blue crystalline solid. The solution is filtered hot, and then cooled to room temperature. After solvent removal, the solid residue is recrystallized from ethanol to yield a purified product, m.p. 117°-119° C.

المصدر