تفاعل #625726

معادلة التفاعل

4-methyl-1,3-benzothiazol-2-amine

3-(cyanomethoxy)-2,6-difluorobenzene carboxamide

→

2,6-Difluoro-3-[(4-methyl-1,3-benzothiazol-2-yl)methoxy]benzenecarboxamide

المردود 36.0%

ظروف التفاعل

الإجراء التجريبي

Synthesised from 4-methyl-1,3-benzothiazol-2-amine and 3-(cyanomethoxy)-2,6-difluorobenzene carboxamide, according to Method K, scheme 26. Yield 36% (second step), mp 201-202° C., HPLC-MS (method 1): m/z 335 [M+H]+, Rt=3.79 min.

المصدر