تفاعل #62540

معادلة التفاعل

Peracetic acid

quinoline

→

Quinoline N-oxide

ظروف التفاعل

المعالجة

1. 1
   أخرىMuch of the acetic acid was removed from the reaction mixture in vacuo
2. 2
   workup.DISSOLUTIONThe resulting residue was dissolved in methylene chloride (50 mL)
3. 3
   غسيلwashed twice with saturated sodium bicarbonate solution
4. 4
   تجفيفAfter drying over MgSO4 the solvent
5. 5
   أخرىwas evaporated
6. 6
   أخرىthe residue was triturated with ether
7. 7
   ترشيحThe resulting tan solid was collected by filtration

الإجراء التجريبي

Peracetic acid (7.5 mL, 39 mmole, 40%) and quinoline (5 g, 39 mmole) were stirred for 2 hours. Much of the acetic acid was removed from the reaction mixture in vacuo. The resulting residue was dissolved in methylene chloride (50 mL) and washed twice with saturated sodium bicarbonate solution. After drying over MgSO4 the solvent was evaporated and the residue was triturated with ether. The resulting tan solid was collected by filtration. This material was carried on without further characterization.

المصدر