تفاعل #62404

معادلة التفاعل

acetic anhydride

4-bromo-5-fluoro-2-methylphenylamine

→

title compound

N-(4-Bromo-5-fluoro-2-methylphenyl)acetamide

ظروف التفاعل

المعالجة

1. 1
   workup.DISTILLATIONExcess acetic anhydride was distilled off under reduced pressure
2. 2
   غسيلthe precipitated crystals were washed with water

الإجراء التجريبي

73.6 mL of acetic anhydride was added with 80.0 g of 4-bromo-5-fluoro-2-methylphenylamine at room temperature, and stirred at this temperature for 10 minutes. Excess acetic anhydride was distilled off under reduced pressure, and the precipitated crystals were washed with water, to afford 77.6 g of the title compound as colorless crystal.

المصدر