تفاعل #620286

معادلة التفاعل

4-cyclopentylamino-8-methoxy-quinoline-3-carboxylic acid ethyl ester

6-isocyanato-2,3-dihydro-benzo[1,4]dioxine

→

1-Cyclopentyl-3-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-7-methoxy-1H-pyrimido[5,4-c]quinoline-2,4-dione

المردود 40.4%

ظروف التفاعل

الإجراء التجريبي

1-Cyclopentyl-3-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-7-methoxy-1H-pyrimido[5,4-c]quinoline-2,4-dione (18 mg) was prepared from 4-cyclopentylamino-8-methoxy-quinoline-3-carboxylic acid ethyl ester (0.1 mmol) and 6-isocyanato-2,3-dihydro-benzo[1,4]dioxine (0.5 mmol) following general procedure C. LCMS: m/z 446 [M+1]+.

المصدر