تفاعل #61972

معادلة التفاعل

4-hydroxybenzaldehyde

1-bromo-3-chloropropane

potassium carbonate

→

title compound

4-(3-Chloro-propoxy)-benzaldehyde

المذيبات

acetone

ظروف التفاعل

المعالجة

1. 1
   درجة الحرارةwas heated
2. 2
   درجة الحرارةto reflux for 16 h
3. 3
   ترشيحThe resulting mixture was filtered
4. 4
   أخرىthe filtrate was evaporated
5. 5
   workup.DISTILLATIONDistillation of the residue (0.5 mm Hg, 220° C.)

الإجراء التجريبي

A suspension of 4-hydroxybenzaldehyde (40 g), 1-bromo-3-chloropropane (63 mL), and potassium carbonate (136 g) in acetone (920 mL) was heated to reflux for 16 h. The resulting mixture was filtered, and the filtrate was evaporated. Distillation of the residue (0.5 mm Hg, 220° C.) gave the title compound as a pale yellow oil that crystallized on standing (46 g).

المصدر