تفاعل #619205

ord-c1ffc0ffd946460a9a4a64b52ebaeff6

معادلة التفاعل

N#CSc1cnc(NC(=O)N(C2CCCCC2)C2CCCCC2)s1
1,1-dicyclohexyl-3-(5-thiocyanato-thiazol-2-yl)-urea
O[C@H](CS)[C@@H](O)CS
dithioerythritol
ClCCc1nnn[nH]1
5-(2-chloroethyl)-1H-tetrazole
→
O=C(Nc1ncc(SCCc2nnn[nH]2)s1)N(C1CCCCC1)C1CCCCC1
1,1-Dicyclohexyl-3-{5-[2-(1H-tetrazol-5-yl)-ethyl-sulfanyl]-thiazol-2-yl}-urea

المتفاعلات

N#CSc1cnc(NC(=O)N(C2CCCCC2)C2CCCCC2)s1
1,1-dicyclohexyl-3-(5-thiocyanato-thiazol-2-yl)-urea
O[C@H](CS)[C@@H](O)CS
dithioerythritol
ClCCc1nnn[nH]1
5-(2-chloroethyl)-1H-tetrazole

الكواشف

لا شيء

ظروف التفاعل

الظروف التفصيلية
See reaction.notes.procedure_details.

المعالجة

  1. 1
    أخرىPrepared

الإجراء التجريبي

Prepared as described in general procedure (H) using 1,1-dicyclohexyl-3-(5-thiocyanato-thiazol-2-yl)-urea, dithioerythritol and 5-(2-chloroethyl)-1H-tetrazole.

المصدر

DOI: 10.6084/m9.figshare.5104873.v1براءة الاختراع: USRE045183E1uspto-grants-2014_10