تفاعل #61835

معادلة التفاعل

1-(naphth-1-yl)-1-propanone

phenyltrimethylammonium tribromide

→

2-bromo-1-(naphth-1-yl)-1-propanone

المردود 175.6%

المذيبات

tetrahydrofuran

ظروف التفاعل

المعالجة

1. 1
   أخرىthen partitioned between petroleum ether and aqueous sodium carbonate solution
2. 2
   أخرىThe organic layer was separated
3. 3
   غسيلwashed with water, brine
4. 4
   تجفيفdried with sodium sulphate
5. 5
   ترشيحfiltered
6. 6
   أخرىevaporated in vacuo

الإجراء التجريبي

To a solution of 1-(naphth-1-yl)-1-propanone (4.0 g) in anhydrous tetrahydrofuran (50 ml) was added phenyltrimethylammonium tribromide (8.0 g). The resulting mixture was stirred overnight at room temperature then partitioned between petroleum ether and aqueous sodium carbonate solution. The organic layer was separated, washed with water, brine, dried with sodium sulphate, filtered and evaporated in vacuo to yield crude 2-bromo-1-(naphth-1-yl)-1-propanone (5.7 g).

المصدر