تفاعل #61829

معادلة التفاعل

2-chloro-5-(trifluoromethyl)-1H-benzo[d]imidazole

2-amino-8-hydroxyquinoline

→

title compound

8-(5-(Trifluoromethyl)-1H-benzo[d]imidazol-2-yloxy)quinolin-2-amine

ظروف التفاعل

المعالجة

1. 1
   أخرىprepared

الإجراء التجريبي

The reaction of 2-chloro-5-(trifluoromethyl)-1H-benzo[d]imidazole (66 mg, 0.3 mol, prepared according to the procedure described in WO 2004/035549 A1) with 2-amino-8-hydroxyquinoline (48 mg, 0.3 mmol, Fluka) under the condition of Example 1 afforded the title compound as an amorphous solid. MS (ESI, pos. ion) m/z: 345 (M+1).

المصدر