تفاعل #61828

معادلة التفاعل

7-bromo-2-chloro-5-(trifluoromethyl)-1H-benzo[d]imidazole

5-amino-2-naphthol

→

title compound

المردود 57.0%

5-(7-Bromo-5-(trifluoromethyl)-1H-benzo [d]imidazol-2-ylamino)naphthalen-2-ol

المردود 57.0%

ظروف التفاعل

المعالجة

1. 1
   أخرىprepared

الإجراء التجريبي

The reaction of 7-bromo-2-chloro-5-(trifluoromethyl)-1H-benzo[d]imidazole (240 mg, 0.8 mmol, prepared according to the procedure described in WO 2004/035549 A1) with 5-amino-2-naphthol (64 mg, 0.4 mmol, TCI-US) under the condition of Example 2 afforded the title compound (57%) as an amorphous solid. MS (ESI, pos. ion) m/z: 423 (M+1).

المصدر